Diagnosis of human cell lymphotropic virus HTLV-1/2 infection

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Diagnosis of human cell lymphotropic virus HTLV-1/2 infection
Problem

There is a lack of methodologies for the universal and differential diagnosis of HTLV-1/2 (human T-cell lymphotropic virus). The high cost of the tests available for the differential diagnosis of HTLV-1/2 infection represents a major challenge in controlling diseases associated with this virus, such as leukemia and neurological problems. It is estimated that there are more than 10 million cases of HTLV in the world.

Solution

The technology consists of a serological immunofluorescence method using flow cytometry for the universal and differential diagnosis of HTLV-1 and HTLV-2 infection. The solution is based on the simultaneous analysis of IgG1 antibody reactivity. The method allows confirmatory diagnosis of the disease in just one step, without the need to collect different types and samples. This methodology can still be used as a more accurate prognosis for the patient. In other words, it is possible to check how the disease progresses in each patient.

Differential
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Single platform
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High sensitivity and specificity
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Easy execution
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Development stage
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What we are searching for

Technology licensing agreement

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Inventors
Olindo Assis Martins Filho
Currículo Lattes de Olindo Assis Martins Filho
Andrea Teixeira de Carvalho
Currículo Lattes de Andrea Teixeira de Carvalho
Kelly Alves Bicalho Carvalho
Currículo Lattes de Kelly Alves Bicalho Carvalho
Jordana Grazziela Alves Coelho dos Reis
Currículo Lattes de Jordana Grazziela Alves Coelho dos Reis
Vanessa Peruhype Magalhães Pascoal
Currículo Lattes de Vanessa Peruhype Magalhães Pascoal
Luciene Pimenta de Paiva
Currículo Lattes de Luciene Pimenta de Paiva
Julia Pereira Martins
Currículo Lattes de Julia Pereira Martins
Hassan Martins Magalhães
Currículo Lattes de Hassan Martins Magalhães
Bruno Caetano Trindade
Currículo Lattes de Bruno Caetano Trindade
Luiz Carlos Júnior Alcantara
Currículo Lattes de Luiz Carlos Júnior Alcantara
Ester Cerdeira Sabino
Currículo Lattes de Ester Cerdeira Sabino
Anna Barbara de Freitas Carneiro Proietti
Currículo Lattes de Anna Barbara de Freitas Carneiro Proietti
Intellectual Property
Type:
Invention Patent
Description
Patent application filed in Brazil
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localizacao
Campus Fiocruz Maré - Av. Brasil, 4036 - Maré, Rio de Janeiro - RJ
portfolio@fiocruz.br
telefone
+55 (21) 3282-9080