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After 6 years of the epidemic that put Northeast Brazil in its epicenter, the Zika virus and its consequences may be away from the spotlight, but it is still a burden that needs to be addressed. From March 15th to18th, researchers from the four corners of the world who participated in one of the greatest Zika research consortiums gathered virtually (due to the current pandemic) to discuss its results and ways forward. The event marked the closing of the project, which promoted studies in a variety of areas from clinical research, to entomology and social science research.
Researchers…
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A methodology that aims to make the monitoring of the new coronavirus variants simpler and faster, besides being cheaper, has just been developed at Fiocruz Pernambuco. It is based on a technique that is already widely used and available in Brazil and in the world, the Sanger sequencing - also called sequencing by capillary electrophoresis. The article with this finding has just been made available online as a preprint on the MedRxiv platform.
Matheus Bezerra e Viviane Carvalho (Photo: Ascom/Fiocruz PE)
The test was developed by the Fiocruz Pernambuco team that monitors Sars-CoV-…
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On April 14, the Oswaldo Cruz Foundation will hold the first PrInt Fiocruz-Capes virtual seminar in 2021. The event is part of a series of integrated seminars between researchers from Fiocruz and Germany, with a diverse thematic. The meeting will be held from 9 am to 11:30 am (Brasilia Time), with transmission through the Fiocruz channel on YouTube.
The seminar, which is aimed at Fiocruz students, seeks to stimulate interest in scientific and cultural training associated with other countries. During the year, meetings will also be organized for more direct contact with German foundations and…
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A paper to be published in May in the U.S. Centers for Disease Control and Prevention's (CDC/US) journal Emerging Infectious Diseases (EID) shows that a first exposure to COVID-19 in mild or asymptomatic cases may not produce an immune response, and that a person can reinfect himself or herself with the same variant. The second infection can cause stronger symptoms than the first, the study indicates.
(Photo:Isabela Carrari - Prefeitura de Santos)
The article Genetic Evidence and Host Immune Response in Persons Reinfected with SARS-CoV-2, Brazil was coordinated by researcher…
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With the start of Oxford/AstraZeneca-Fiocruz production vaccine on national territory, and the batches delivery to the Ministry of Health, this stage is beginning to give its first results to Brazilian society. Still this year, the country will have a vaccine produced entirely in Brazil and already in this first semester the manufacture of the first batches of the active pharmaceutical ingredient (API) will start, which should be available to the population in the second semester. It will be a vaccine 100% produced in Brazil. But Fiocruz continues, in a complementary way, to support the…
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The Bulletin of the Fiocruz Covid-19 Observatory, released on March 26, shows that the country is facing the collapse of the health system. At the same time, the pandemic is now taking up new shapes, affecting younger age groups: 30 to 39 years old, 40 to 49, and 50 to 59. In such a scenario, researchers defend the adoption of measures in two interconnected groups.
The first group includes urgent measures that involve the containment of the rates of transmission and growth of cases by employing blocking or lockdown measures, accompanied by the increased number of beds with quality and safety…
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This March 2021, the Pan American Health Organization/World Health Organization (PAHO/WHO) designated the National Institute for Women's, Children's and Adolescent Health Fernandes Figueira (IFF/Fiocruz) as a PAHO/WHO Collaborating Center to strengthen Human Milk Banks. The designation as a Collaborating Center will be valid for a four years period, starting on March 3, 2021, and can be renewed by redesignation.
The designation as a Paho/WHO partner is valid for four years (Photo: Peter Ilicciev)
A Collaborating Center is an institution designated by the World Health Organization…
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Executive:
Viviane Santos de Oliveira Veiga
Fundação Oswaldo Cruz (FIOCRUZ)
Maria Luiza Machado Campos
Universidade Federal do Rio de Janeiro (UFRJ)
João Luiz Rebelo Moreira
University of Twente (International Representative)
Patricia Corrêa Henning
Universidade Federal do Estado do Rio de Janeiro (UNIRIO)
Luiz Olavo Bonino da Silva Santos
VODAN IN consultant
Researchers:
Sergio Manuel Serra da Cruz
Universidade Federal do Rio de Janeiro (UFRJ)
Giseli Rabello Lopes
Universidade Federal do Rio de Janeiro (UFRJ)
Development:
Vânia Jesus de Araujo Soares Borges
Universidade Federal…
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Universidade Federal do Estado do Rio de Janeiro (UNIRIO)
Carlos Roberto Lyra da Silva - Universidade Federal do Estado do Rio de Janeiro (UNIRIO)
Gaffree Guinle Hospital
Romero de Melo Silva - Universidade Federal do Estado do Rio de Janeiro (UNIRIO)
Sérgio Luis Teixeira de Aquino - Universidade Federal do Estado do Rio de Janeiro (UNIRIO)
Jorge da Cunha Barbosa Leite - Universidade Federal do Estado do Rio de Janeiro (UNIRIO)
Municipal São José de Duque de Caxias Hospital
Antonio Pontes Neto - Hospital Municipal São José de Duque de Caxias
Carlos Antonio da Silva - Hospital Municipal…
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The VODAN Brazil Implementation Network was established through the efforts of teams from the Oswaldo Cruz Foundation (Fiocruz), Federal University of Rio de Janeiro (UFRJ), Federal University of the State of Rio de Janeiro (UNIRIO) and São José Municipal Hospital. The Vodan Brazil aims to provide an infrastructure capable of enabling health units to collect and manage medical data of patients infected with COVID-19.
During the first phase of the project, a collection of patient data from each hospital is collect using the COVID-19 CASE RECORD FORM, adopted by the World Health…
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Scientists at the Fiocruz Genomics Network have identified important changes in the Spike (S) protein structure of the Sars-CoV-2 virus circulating in Brazil. Eleven gene sequences showed deletions (loss of genetic material) in the initial region of the protein and in four there was some amino acids insertion. The Spike protein is associated with the pathogen's ability to enter human cells and is one of the main targets of the neutralizing antibodies produced by the body to block the virus.
Photo:Josué Damacena, IOC/Fiocruz
The discovery is the result of genomic surveillance conducted…
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Science formulated with collaboration and transparency. On March 17th, the Oswaldo Cruz Foundation (Fiocruz) presented the advances in the implantation of the Institutional Data Repository for Research - Arca Dados, an important element to implement the Policy for Management, Sharing and Opening of Data for Research. The document (approved in September 2020 by the Deliberative Council of Fiocruz and whose Ordinance came into term in December) is now available in a publication in Portuguese and English: you can access both versions here.
By printing its principles and guidelines, the…
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The United Kingdom ambassador in Brazil, Peter Wilson, visited the Oswaldo Cruz Foundation (Fiocruz) on March 5 for a meeting with the president of the institution, Nísia Trindade Lima, and to visit the Immunobiological Technology Institute (Bio-Manguinhos) plant that is producing the Covid-19 Fiocruz vaccine.
Photo: Pedro Paulo Gonçalves
“I greatly admire the work you have you been doing, and we are here to know how we can help”, explained the Ambassador. Fiocruz president stated that Fiocruz has “a historical partnership with the United Kingdom and the pandemic has highlighted the…
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Edgar Marcelino de Carvalho, a researcher of Fiocruz Bahia, was considered the world’s greatest specialist in cutaneous leishmaniasis by the site Expertscape. The ranking was based on science publications: Carvalho published 84 papers on the subject between 2010 and 2021. The ranking includes the 66 scientists with most papers published on cutaneous leishmaniasis from all over the world and also includes three other researchers of Fiocruz Bahia, Lucas Pedreira de Carvalho, Aldina Prado Barral, and Manoel Barral-Netto.
In the field of cutaneous leishmaniasis, no other institution has better…
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Six years after the National Health Emergency declared by the Brazilian Ministry of Health, Zika is still a public health issue that mobilizes many actors in society. Fiocruz is launching the virtual exhibition Zika: lives affecting lives, produced by the Zika Social Sciences Network and the Oswaldo Cruz House (COC/Fiocruz), through the Museum of Life. The exhibition is the result of collaborative scientific research, produced with intense social participation, and its goal is to raise awareness regarding the fact that Congenital Zika Virus Syndrome (CZVS) goes beyond microcephaly, which is…
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Faced with the current pandemic scenario, Fiocruz released this Tuesday (March 16), another edition of the Fiocruz COVID-19 Observatory Extraordinary Bulletin. The analysis draws attention to the indicators that point to an extremely critical situation across the country. In the view of the researchers who carry it out, this is the biggest health system collapse in the history of Brazil.
The Bulletin shows that, at the moment, of the 27 federative units, 24 states and the Federal District have occupancy rates for ICU COVID-19 beds for adults in the Brazilian Public Health System (SUS,…
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On March 11, one year since the World Health Organization (WHO) declared that the COVID-19 epidemic represented a global pandemic, the new Bulletin of the COVID-19 Observatory Fiocruz highlights that Brazil is among the countries with the worst indicators. The country totals 11,122,429 cases and 268,370 deaths, which corresponds to 9.5% and 10.3% of the global total, respectively, even though the Brazilian population is less than 3% of the world's population.
In a context in which Brazil faces the worst scenario since the pandemic began, researchers at the COVID-19 Fiocruz Observatory,…
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The Brazilian Health Regulatory Agency (Anvisa) granted the definitive registration of the COVID-19 Fiocruz vaccine on March 12. Thus, Fiocruz becomes the first holder of a registration of a COVID -19 vaccine produced in the country and adds to its product portfolio the eleventh vaccine to be supplied to the National Immunization Program (PNI). With the registration, the expectation is that Anvisa will authorize the release of the first batches week so that, Fiocruz can deliver to PNI the first one million Covid-19 vaccines produced by the institution.
"Just six months after signing…
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A Fundação Oswaldo Cruz (Fiocruz) lançou (5/3) o boletim da pesquisa Monitoramento da saúde, acesso à EPIs de técnicos de enfermagem, agentes de combate às endemias, enfermeiros, médicos e psicólogos, no município do Rio de Janeiro em tempos de Covid-19. O documento foi desenvolvido pela equipe da pesquisa, que conta com doze professoras-pesquisadoras da Escola Politécnica de Saúde Joaquim Venâncio (EPSJV/Fiocruz), em parceria com pesquisadores do Instituto de Comunicação e Informação Científica e Tecnológica em Saúde (Icict/Fiocruz), do Núcleo de Saúde do Trabalhador (Nust/Fiocruz…
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In an extraordinary edition of its Bulletin, the Covid-19 Fiocruz Observatory publishes an updated of the historical series on the occupation of COVID-19 ICU beds for adults in the Brazilian Health System (SUS, in the Portuguese acronym), with data obtained on Monday (8/3). The analysis presents rates verified since July 17th, 2020, and aims to alert to the critical scenario of the country. Check out the full document (in Portuguese).
According to the Bulletin, of the total of 27 capitals of the country, 25 have occupancy rates of COVID-19 ICU beds for adults equal to or greater than 80%, 15…
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Fiocruz president, Nísia Trindade Lima, participated in a World Health Organization (WHO) discussion on how investing in research on Covid-19 treatments can increase cooperation at national and international levels, on March 3. The discussion table, named Towards a Shared Research Agenda, included in the debate on how to identify knowledge gaps and research priorities for COVID-19 treatments, to incentivize cooperation and coordination for the priorities identified.
In her speech, the president mentioned six items for discussion, based on the experience of Fiocruz and of the Evandro…
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Many affluent countries, with the necessary technological capabilities and expertise, entered into the production of Covid-19 vaccines or sought the biopharmaceutical companies to block them for themselves through anticipated buying. It is estimated that as early December 2020, 3.8 billion vaccine doses had been guaranteed to these countries by several producers. If one compares that figure with the 3.2 billion doses, that include the 700 million doses from the Covax facility, for the rest of the world one cannot help being struck by the immensity of the inequity. The USA and the UK, for…
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In a technical release issued last Thursday (March 3) by the Fiocruz Covid-19 Observatory, researchers warn of the geographical dispersion, in the territory, of “worrying variants” and of their high prevalence in the three Brazilian regions under study (South, South-East and North-East).
The new RT-PCR protocol, developed by Fiocruz Amazônia, was used by Fiocruz diagnostic support units and testing stations to evaluate about one thousand samples from the states of Alagoas, Minas Gerais, Pernambuco, Paraná, Rio de Janeiro, Rio Grande do Sul and Santa Catarina. The protocol…
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When the first Portuguese and Spanish ships moored along the coast of the Americas, microorganisms that caused common disease in Europe, but which had never occurred in American soil, disembarked along with the crews. The causer of visceral leishmaniasis, Leishmania infantum is part of a group of microscopic travelers which, despite the huge differences between the Old and the New World, managed to settle here quite well.
More than 500 years later, a study suggests that the evolution of this pathogen in the tropics has followed a surprising trajectory. Leishmaniasis that…
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A pioneering study used the genomic sequencing of samples of Mycobacterium tuberculosis to assess the resistance of indigenous peoples to anti-tuberculosis drugs. Published on Scientific Reports, a magazine of the Nature group, the research also revealed a high frequency of polymorphisms associated with resistance to the main drugs used in the treatment. The article, titled Identification of a predominant genotype of Mycobacterium tuberculosis in Brazilian indigenous population, boasts the participation of researchers Paulo Basta and Reinaldo Santos, of the…
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An important step to understanding the dynamics of arbovirus transmission, such as dengue fever, zika and chikungunya, is to get to know mosquitoes’ ability to get infected and to transmit the viruses that cause these diseases. This characteristic is technically known as vectorial competence. A study by researchers of the Oswaldo Cruz Institute (IOC/Fiocruz) showed that the Aedes aegypti has low vectorial competence for the zika virus when feeding directly on infected monkeys. The work suggests that virus transmission is much more affected by the high density of the insect in a certain region…
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A study of the Oswaldo Cruz Institute (IOC/Fiocruz) was received the Small Grants award of the Royal Society of Tropical Medicine and Hygiene (RSTMH). The research was made by post-doctorate student Viviane de Almeida Bastos, under the supervision of researchers Ana Gisele Ferreira and Richard Hemmi Valente, of the IOC’s Toxicology Laboratory, and investigates natural inhibitors of snake toxins, isolated from South American opossum Didelphis aurita, using the mass spectrometry technique.
“Our intention is to map the regions of the antiphonic proteins involved in the inhibition of…
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