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The pandemic brought challenges, but also opportunities, according to lecturers on the 6th annual Multi-stakeholder Forum on Science, Technology, and Innovation for the Sustainable Development Goals (SDG), also known as the STI Forum. In Lessons from the COVID-19 Pandemic, the forum’s first session, on Tuesday May 4th, specialists on the fields of sciences, technology and economics analyzed the scenario and looked for ways to recover and prevent a new global sanitation crisis. Among them was the President of Fiocruz, Nísia Trindade Lima.
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The director of Fiocruz Minas, Zélia Profeta, was invited to be a member of the Council on the Economics of Health for All, recently created by the World Health Organization (WHO). The invitation was sent by WHO’s Director-General Tedros Adhanom and Professor Mariana Mazzucato of University College London, who will coordinate the Council.
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A study by Fiocruz and WWF-Brasil shows that the wildfires in the Amazon were responsible for the increase in the percentages of hospitalizations due to respiratory problems in the last 10 years (2010-2020) in states with higher numbers of hot spots: Pará, Mato Grosso, Rondônia, Amazonas and Acre.
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Two drugs used against hepatitis C have been proven effective in inhibiting Sars-CoV-2 replication in cells in laboratory studies. The trial is now entering its phase 2: tests in patients. The results of the first phase of the trial, led by researchers of the Oswaldo Cruz Foundation (Fiocruz), were published on April 21 in a paper for the Journal of Antimicrobial Chemotherapy, by Oxford Academic. The results of phase 2 will likely be known in the second semester of 2021.
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The Presidency of the Oswaldo Cruz Foundation (Fiocruz) signed, on April 20, an international cooperation agreement with the Institute of Global Health of Barcelona (ISGlobal), to establish the basis to implement a joint work plan for the upcoming years. The two institutions have worked together at previous occasions in different research projects and scientific publications.
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Published on April 24, the Bulletin of the Fiocruz COVID-19 Observatory, referring to Epidemiological Weeks (EW) 14 and 15, between 4 and 17 April, presents a general overview of the Covid-19 situation in the country and its implications. The new edition shows that the pandemic is hitting younger people. The number of cases and deaths by Covid-19 per age group shows that the differential increase per age group is steady.
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A study by researchers of the Oxford University shows that the risk of cerebral venous thrombosis (CVT) in people with COVID-19 is considerably higher than in those who have been vaccinated with mRNA (messenger RNA) vaccines, such as those by Pfizer and Moderna. In addition to mRNA vaccines, the analysis also included the Oxford/AstraZeneca immunizer, produced in Brazil by the Oswaldo Cruz Foundation (Fiocruz).
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The emergence of COVID-19 and the entire context of the pandemic humankind has been facing has raised an alert for the possible appearance of other emerging and re-emerging epidemics that may occur as a consequence of the interferences suffered by Brazilian biomes — deforestation and destruction of ecosystems.
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Remembered for the second consecutive year, World Chagas Disease Day was marked in Fiocruz on 14/4, with an event that had not only tributes to those who helped in the research and fight against the disease, but also with the look on the future. In addition to the tributes to the researchers of the institution Zilton Andrade and José Rodrigues Coura, who have died, there was the agreement with Unitaid of CUIDA Chagas virtual signing, a project that aims to eliminate the disease congenital transmission in Latin American countries.
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A “pandemic of inequalities”, which denies people access to water to wash their hands, is one of the factors that have worsened the dissemination of Sars-CoV-2 in Latin America and in the Caribbean. This is the assessment of the UN High Commissioner for Human Rights and former president of Chile, Michelle Bachelet. A physician herself, last Thursday (April 15) she opened the Advanced Seminaries on Global Health and Health Diplomacy of the Center of International Relations in Health (Cris/Fiocruz).
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The Conference On Expanding Africa’s Vaccine, organized by the African Union and the Centers for Disease Control in Africa (CDC Africa), held on 12 and 13/4, had the Oswaldo Cruz Foundation (Fiocruz) president as one of the speakers on Tuesday. During Session 8, on the Partnership with Foundations for Vaccine Production, Nísia reaffirmed Fiocruz's commitment to a South-South agenda to support the needs of the African continent in strengthening its health system, preparing for disease emergencies, and providing the population with access to medical care.
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Many viruses can hamper coagulation, including those that cause dengue fever and yellow fever. In more severe cases, they may lead to bleeding. This is why these diseases are considered hemorrhagic viral fevers.
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After 6 years of the epidemic that put Northeast Brazil in its epicenter, the Zika virus and its consequences may be away from the spotlight, but it is still a burden that needs to be addressed. From March 15th to18th, researchers from the four corners of the world who participated in one of the greatest Zika research consortiums gathered virtually (due to the current pandemic) to discuss its results and ways forward. The event marked the closing of the project, which promoted studies in a variety of areas from clinical research, to entomology and social science research.
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A methodology that aims to make the monitoring of the new coronavirus variants simpler and faster, besides being cheaper, has just been developed at Fiocruz Pernambuco. It is based on a technique that is already widely used and available in Brazil and in the world, the Sanger sequencing - also called sequencing by capillary electrophoresis.
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On April 14, the Oswaldo Cruz Foundation will hold the first PrInt Fiocruz-Capes virtual seminar in 2021. The event is part of a series of integrated seminars between researchers from Fiocruz and Germany, with a diverse thematic. The meeting will be held from 9 am to 11:30 am (Brasilia Time), with transmission through the Fiocruz channel on YouTube.
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A paper to be published in May in the U.S. Centers for Disease Control and Prevention's (CDC/US) journal Emerging Infectious Diseases (EID) shows that a first exposure to COVID-19 in mild or asymptomatic cases may not produce an immune response, and that a person can reinfect himself or herself with the same variant. The second infection can cause stronger symptoms than the first, the study indicates.
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With the start of Oxford/AstraZeneca-Fiocruz production vaccine on national territory, and the batches delivery to the Ministry of Health, this stage is beginning to give its first results to Brazilian society. Still this year, the country will have a vaccine produced entirely in Brazil and already in this first semester the manufacture of the first batches of the active pharmaceutical ingredient (API) will start, which should be available to the population in the second semester. It will be a vaccine 100% produced in Brazil.
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The Bulletin of the Fiocruz Covid-19 Observatory, released on March 26, shows that the country is facing the collapse of the health system. At the same time, the pandemic is now taking up new shapes, affecting younger age groups: 30 to 39 years old, 40 to 49, and 50 to 59.
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This March 2021, the Pan American Health Organization/World Health Organization (PAHO/WHO) designated the National Institute for Women's, Children's and Adolescent Health Fernandes Figueira (IFF/Fiocruz) as a PAHO/WHO Collaborating Center to strengthen Human Milk Banks. The designation as a Collaborating Center will be valid for a four years period, starting on March 3, 2021, and can be renewed by redesignation.
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Executive:
Viviane Santos de Oliveira Veiga
Fundação Oswaldo Cruz (FIOCRUZ)
Maria Luiza Machado Campos
Universidade Federal do Rio de Janeiro (UFRJ)
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Universidade Federal do Estado do Rio de Janeiro (UNIRIO)
Carlos Roberto Lyra da Silva - Universidade Federal do Estado do Rio de Janeiro (UNIRIO)
Gaffree Guinle Hospital
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The VODAN Brazil Implementation Network was established through the efforts of teams from the Oswaldo Cruz Foundation (Fiocruz), Federal University of Rio de Janeiro (UFRJ), Federal University of the State of Rio de Janeiro (UNIRIO) and São José Municipal Hospital. The Vodan Brazil aims to provide an infrastructure capable of enabling health units to collect and manage medical data of patients infected with COVID-19.
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Scientists at the Fiocruz Genomics Network have identified important changes in the Spike (S) protein structure of the Sars-CoV-2 virus circulating in Brazil. Eleven gene sequences showed deletions (loss of genetic material) in the initial region of the protein and in four there was some amino acids insertion. The Spike protein is associated with the pathogen's ability to enter human cells and is one of the main targets of the neutralizing antibodies produced by the body to block the virus.
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Science formulated with collaboration and transparency. On March 17th, the Oswaldo Cruz Foundation (Fiocruz) presented the advances in the implantation of the Institutional Data Repository for Research - Arca Dados, an important element to implement the Policy for Management, Sharing and Opening of Data for Research.
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The United Kingdom ambassador in Brazil, Peter Wilson, visited the Oswaldo Cruz Foundation (Fiocruz) on March 5 for a meeting with the president of the institution, Nísia Trindade Lima, and to visit the Immunobiological Technology Institute (Bio-Manguinhos) plant that is producing the Covid-19 Fiocruz vaccine.
Photo: Pedro Paulo Gonçalves
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Edgar Marcelino de Carvalho, a researcher of Fiocruz Bahia, was considered the world’s greatest specialist in cutaneous leishmaniasis by the site Expertscape. The ranking was based on science publications: Carvalho published 84 papers on the subject between 2010 and 2021.
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