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Oswaldo Cruz Foundation was created on May 25, 1900. It was first called Serum Therapeutic Institute. Initially the objective was produce serums and vaccines against the plague. After the designation of Oswaldo Cruz as director in 1902, the institution expanded its activities and became involved in research and experimental medicine The foundation became the base for Oswaldo Cruz’s famous sanitation campaigns in Rio de Janeiro. That time the city suffered with epidemics of bubonic plague, yellow fever and smallpox. After bypass the critical situation in Rio, the foundation made scientific…
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Re-elected president of Fiocruz, Mario Moreira took office on April 4th for another four years. Re-elected on October 24th for the 2025-2028 term, he received 81.8% of the valid votes. The ceremony was held outdoors at the Pasteur Square, next to the famous Manguinhos Castle in Rio de Janeiro. Mario Moreira, the 28th president of Fiocruz, began his second term with the most diverse ethnic-racial and gender composition in the Foundation's history. Of the top management positions, including vice presidents and coordinators, 64% will be occupied by black people. Women will be in the majority,…
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The Immunobiological Technology Institute (Bio-Manguinhos/Fiocruz) will take part in an unprecedented initiative by the Ministry of Health to expand access to rapid and long-acting insulin analogues for patients with type 2 diabetes in Primary Health Care. The Institute will play a key role in the Productive Development Partnership (PDP) for insulin glargine, formalized by the Ministry of Health on 4/2, in partnership with the biotechnology company Biomm and the Chinese pharmaceutical company Gan&Lee, so that the product becomes 100% national, reducing foreign dependence. Representatives…
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A research carried out at the Carlos Chagas Institute (ICC/Fiocruz Paraná) opens up new perspectives for the treatment of acute lymphoid leukemia (ALL), the most common type of cancer in childhood. The work resulted in patents being granted in China in July 2024 and in the United States in December. The technology is still being analyzed for a patent in Canada, India, and the European Community. The discovery, made by researchers Tatiana Brasil and Nilson Zanchin and PhD student Stephanie Bath de Morais, proposes an innovative version of the human enzyme asparaginase, making the treatment…
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President of Fiocruz, Mario Moreira was elected president of the Pasteur Network last Friday (April 4). He succeeds Amadou Sall, CEO of the Institut Pasteur de Dakar (Senegal). The Foundation has been part of the Pasteur Network since 2009 and became an official member in 2015; since then, it has been forging a path of cooperation in support of science, production, innovation, and the training of new talents for accessible healthcare for all, globally. Recent years have demonstrated such efforts and Fiocruz's leadership role: in 2024, Moreira was elected as the regional representative of the…
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The President of Fiocruz, Mario Moreira, was honored as Commander of the Order of the Crown, one of the highest honors conferred by the King of Belgium, on Thursday (April 3). Established at the end of the 19th century, the title is granted to citizens who have rendered significant services to the Belgian state, particularly those who promote the life and rights of individuals. The ambassador of Belgium in Brazil, Peter Claes, the president of Fiocruz, Mario Moreira, and the consul-geral of Belgium, Caroline Mouchart (photo: Peter Ilicciev) In addition to honoring the work of Fiocruz, the…
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In an initiative that positions Ceará as a leading player in international scientific cooperation, Fiocruz, the Pasteur Institute, and the Federal University of Ceará (UFC) signed a Memorandum of Understanding (MoU) last Tuesday (3/25) aimed at research, innovation, and training in the field of health. The ceremony took place at the Pasteur-Fiocruz Center for Immunology and Immunotherapy, in Eusébio (CE), and marked the consolidation of a strategic partnership between Brazil and France. The director of the UFC, Custódio Almeida, the co-coordinators of the Pasteur-Fiocruz Center for…
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The National School of Public Health (ENSP/FIOCRUZ) and the Global Health Research Center of the Guangdong University of Foreign Studies in China will sign a cooperation agreement to tackle Minamata disease and mercury exposure among indigenous populations. The joint actions were discussed during the visit of the honorary professor of the Chinese institution, Kunihiko Yoshida, to Ensp/Fiocruz on March 19th and 20th. He was welcomed by the researchers and coordinators of the Environment, Diversity and Health group, Paulo Basta and Sandra Hacon, and by the International Cooperation advisor at…
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A review article led by researchers from the Oswaldo Cruz Institute (IOC/Fiocruz) analyzes scientific evidence on the impact of the exposure of pregnant women to two types of chemical substances, which can damage the formation of the central nervous system of babies. Published in the Journal of Hazardous Materials, the study was carried out in partnership with scientists from the Florida International University and the University of Miami in the United States. Used in various industrial processes and present in everyday products – such as non-stick pans, fire-fighting foams, waterproof and…
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Brazilian and foreign researchers dedicated to clinical trials in the country - or even abroad - can, as of 03/24, count on the help of Rebec@, the world's first generative artificial intelligence tested and trained to assist in the registration of clinical trials according to the guidelines of the global network International Clinical Trials Registry Platform (ICTRP), the World Health Organization's gold standard for information transparency. Rebec@ is one of the many innovations of the Brazilian Registry of Clinical Trials (ReBEC), a trilingual platform managed by Fiocruz's Vice-Presidency…
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A study coordinated by Fiocruz Amazônia on the problem of double burden of malnutrition among children in rural and urban areas of hard-to-reach municipalities in the state of Amazonas raises an alarm for the situation of children under 5, especially the most vulnerable in the context of climate crisis, as direct impacts on their growth and development are expected, as well as later negative effects in adulthood. The study, recently published in the scientific journal Frontiers Public Health, was carried out by researchers from various institutions, such as the Lancaster University (UK), the…
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A new study carried out by researchers from the National Institute of Women, Children and Adolescents Health Fernandes Figueira (IFF/Fiocruz) highlights the benefits of exclusive breastfeeding in strengthening babies' immunity against COVID-19. The research, which involved women vaccinated against the virus, revealed that human milk contains significant levels of neutralizing antibodies, especially among mothers who breastfeed exclusively. The study by IFF/Fiocruz researchers Yasmin Amaral, Antonio Egídio Nardi, Daniele Marano, Ana Carolina da Costa, and Maria Elisabeth Moreira reveals that…
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On Tuesday (2/25), the Brazilian Ministry of Health announced that Fiocruz and the company Biomm will enter into a production development partnership for the fully national manufacture of insulin glargine. Scheduled for distribution to the Unified Health System (the Brazilian national public system, SUS) in the second half of 2025, the measure is part of the Productive Development Partnerships (PDP) Program. It involves the production of the Active Pharmaceutical Ingredient (API) by the Fiocruz's Immunobiological Technology Institute (Bio-Manguinhos/Fiocruz) at the Strategic Inputs Technology…
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The National Council for Scientific and Technological Development (CNPq), the Oswaldo Cruz Foundation (Fiocruz), through the Oswaldo Cruz House (COC), and the Portuguese Foundation for Science and Technology (FCT) are launching a call for the International Research Excellence Program of the Oswaldo Cruz House (PROEP-INTER 2025) The notice was published last Friday (2/21) in the Federal Official Gazette by the CNPq. Because of its importance, the agreement was mentioned in the Joint Declaration, an official document that reflects the commitments and understandings established during the 14th…
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The World Health Organization (WHO) launched the Collaborative Open Research Consortium (CORC) on Flaviviruses in partnership with Fiocruz in an online event on Monday (2/24). The CORCs are a new strategy for the organization, through its Research and Development (R&D) Blueprint for Epidemics. By focusing on viral families rather than individual pathogens, CORCs aim to create a more comprehensive approach to tackling future health emergencies. For each family chosen, a CORC has been set up, bringing together different experts such as research institutions, medical countermeasure…
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  Animation presents a three-dimensional reconstruction of the 'viral factory' in a cell infected by the mpox virus: dark blue represents the cell nucleus; orange represents mature viral particles; green represents mitochondria; yellow represents rough endoplasmic reticulum; violet represents empty vesicles; purple represents immature viral particles; and light blue represents viral DNA (Image: Barreto-Vieira and collaborators) Researchers from the Oswaldo Cruz Institute (IOC/Fiocruz) have just presented another important contribution to global science: pioneering advances in…
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Fiocruz played a key role in the 14th Brazil-Portugal Summit, that took place on Wednesday (02/19) in Brasília. At the high-level meeting, President Luiz Inácio Lula da Silva discussed with Prime Minister Luís Montenegro bilateral cooperation in various areas, such as health, science and technology, the economy and justice, and celebrated 200 years of diplomatic relations between the two countries. President of Fiocruz, Mario Moreira, participated in the thematic health panel, led by the Health ministers of Brazil, Nísia Trindade Lima, and Portugal, Ana Paula Martins (photo: Pamela Lang)…
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Fiocruz has a strategic role in Science, Technology and Innovation (ST&I) in health in the country, from the formulation of public policies to the delivery of medical products, diagnosis and health processes, always with added value for society. The Vice Presidency of Research and Biological Collections (VPPCB) is responsible for proposing guidelines for institutional research and contributes with investments in ST&I for the generation of knowledge and for the training and qualification of human resources, through internal calls for projects and research grants. VPPCB also coordinates…
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The Vice-Presidency of Environment, Healthcare and Health Promotion (VPAAPS) coordinates, formulates, consolidates and promotes the synergy of actions, actors and units of Fiocruz in the areas of environment, healthcare and health promotion with an integrated manner in order to respond to the needs of the Brazilian National Health System (SUS) considering social determinants of health. This department seeks to foment the evaluation, deployment and management policies that promote sustainable development, expanding access to health and quality of care from social needs, especially in…
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Son of the doctor Bento Gonçalves Cruz and Amália Taborda de Bulhões Cruz, Oswaldo Cruz was born on 5 August 1872 in the city of São Luís de Paraitinga, São Paulo. He lived there until 1877, when his father was transferred to Rio de Janeiro. He studied at the Laure and São Pedro de Alcântara Colleges and at the Dom Pedro II Day School. At the age of fifteen, he was admitted to the Rio de Janeiro Faculty of Medicine. Before finishing the course he had already published two articles on microbiology in the Brasil Médico journal. On 24 December 1892, he qualified as a medical doctor, with a…
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The intense heat in Rio de Janeiro is not just an appeal for going to the beach or a reason for discomfort and stress for those with no way of cooling off. The high temperatures for which the marvelous city is known are related to an increased mortality in the capital of Rio de Janeiro. This is what research by João Henrique de Araujo Morais, a doctoral student at the Sergio Arouca National School of Public Health (Ensp/Fiocruz) and researcher at the Epidemiological Intelligence Center of the Municipal Health Secretariat of Rio de Janeiro, shows. The study conducted by the Public Health…
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In the context of the Year of Brazil in France and France in Brazil, the French ambassador, Emmanuel Lenain, visited Fiocruz on Thursday (2/13) to further consolidate the partnership between the Foundation and the institutions of his country. While this collaboration is already long-standing in the areas of education and research, the idea now is to also advance in production and expand the mobility of researchers. In addition to meeting with president Mario Moreira and members of the Fiocruz Global Health Center (Cris/Fiocruz), Lenain honored Special Advisor to the Presidency Wilson Savino…
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Published in the journal The Lancet Regional Health - Americas, an article by researchers from the Center for Technological Development in Health (CDTS/Fiocruz) points out that 1 in 4 women (25.4%) had to leave the municipality to give birth in hospitals belonging to the Unified Health System (SUS), increasing from 23.6% to 27.3% in the period analyzed. Travel distance and time also increased by 31.1% (54.0 km to 70.8 km) and 33.6% (63.1 min to 84.3 min), respectively. The survey, which mapped more than 6.9 million births between 2010-2011 and 2018-2019, reinforces the existence of…
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Developed with the participation of the Oswaldo Cruz Institute (IOC/Fiocruz), the first molecular diagnostic kit for rotavirus and norovirus in Brazil should contribute to the surveillance of pathogens and the investigation of outbreaks of acute diarrhea. The innovation has been approved by the Brazilian Health Regulatory Agency (Anvisa). The quadriplex test allows for four simultaneous investigations, including rotavirus, two norovirus genogroups and an internal control, which increases the reliability of the results. The kit was developed by the Molecular Biology Institute of Paraná (IBMP)…
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This year marks a decade since the United Nations (UN) established February 11th as the International Day of Women and Girls in Science. The creation of the date draws attention to the importance of seeking gender equity in scientific careers, a space where, for example, the "scissors effect" still prevails: the fact that, although there are already more women than men entering many fields, it is men, and not women, who occupy the majority of leadership positions. Especially in the last decade, there have been important advances in tackling this inequality. We can mention, for example,…
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The executive director of the Pasteur Network, Rebecca Grais, visited Fiocruz on Thursday (2/6) to discuss an even greater role for the Foundation in 2025. Received by president Mario Moreira at the Moorish Castle, she met with members of the Office, the Fiocruz Global Health Center (Cris/Fiocruz), and the Immunobiological Technology Institute (Bio-Manguinhos/Fiocruz) to see what this participation might look like. Rebecca Grais met with Mario Moreira and other members of Fiocruz at the Moorish Castle (photo: Pedro Linger) Elected last year as the Network's regional representative for the…
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Researchers from Fiocruz Bahia have identified the main predictors of tuberculosis incidence in Brazil by analyzing the disease records from January 2018 to December 2023, and have made projections from 2024 to 2030. The results suggest that, although valuable, current public policies are not enough to reduce the burden of tuberculosis, according to the World Health Organization (WHO) elimination plan. The study, coordinated by Fiocruz Bahia researcher Bruno Bezerril, was published in The Lancet Regional Health - Americas to assess the possible impact of strategic public health…
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The World Health Organization (WHO) has launched a new strategy for identifying priority pathogens through the R&D Blueprint Program of the Department of Health Emergencies. The initiative, launched in 2024, highlights research and development (R&D) as a central element in preventing, preparedness for and responding to epidemics and pandemics. In this context, for each priority pathogen family, a Collaborative Open Research Consortium (CORC) will be set up – a global hub made up of different actors from the multilateral public health ecosystem (experts, research institutions, funders…
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Since the end of 2023, several outbreaks of Oropouche fever have occurred in the Region of the Americas. In Brazil alone, there were more than 17,400 cases between 2023 and 2025, according to data from the Ministry of Health. Fulfilling its mission to provide answers to public health, professionals from the Oswaldo Cruz Institute (IOC/Fiocruz) have been contributing to a series of initiatives. The latest is the production of an operational manual to guide teams of entomologists in the Americas in identifying the main taxonomic and ecological characteristics of the insect species that vectors…
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