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A Fundação Oswaldo Cruz, por meio do Instituto de Tecnologia em Imunobiológicos (Bio-Manguinhos/Fiocruz), disponibiliza para o Ministério da Saúde (MS) as primeiras doses da vacina Covid-19 (recombinante) produzidas com o Ingrediente Farmacêutico Ativo (IFA) nacional. O primeiro lote de vacinas nacionais foi liberado pelo controle de qualidade interno de Bio-Manguinhos/Fiocruz no dia 14 de fevereiro.
As pouco mais de 550 mil doses disponibilizadas já compõem as entregas da Fiocruz contratadas pelo Ministério da Saúde para 2022 (foto: Bio-Manguinhos/Fiocruz)
“A liberação das primeiras…
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Depois de um ano de intervalo devido às restrições provocadas pela pandemia de Covid-19, o projeto Fiocruz na Antártica (Fioantar) retomou as expedições científicas ao continente com um novo embarque na manhã desta quarta-feira (13/10). Após uma semana em quarentena com ações para enfrentamento à Covid-19, incluindo execução de testes diagnósticos antes e durante o período, o navio de apoio oceanográfico Ary Rongel partiu rumo à Estação Antártica Comandante Ferraz com o pesquisador Lucas Moreira. Em novembro, mais três pesquisadores do Fioantar - Maria Ogrzewalska, Harrison Magdinier Gomes e…
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With Fiocruz among the signatories, it was launched this Wednesday (October 6), the São Paulo Declaration on Planetary Health, an initiative of Planetary Health Alliance and the University of São Paulo, in partnership with the United Nations Development Programme (UNDP). The declaration is considered the first document of the global planetary health community to describe the actions needed to achieve what it calls "the great transition: a just transformation to a world that optimizes the health and all people and the planet's well-being".
Published on Wednesday in the scientific journal The…
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A new study by Fiocruz on the effectiveness of vaccination in Brazil shows that the population has benefitted from the vaccination plan against the Sars-CoV-2 in the prevention of severe cases and deaths by Covid-19, although effectiveness varies between age groups. The analysis, which also included subjects vaccinated with the first dose of the Pfizer shot, was carried out between January 17 and July 19 this year, a total of six months, in which the Gamma variant was predominant. The study evaluated more than 66 million records and is available in the MedRxiv online repository as preprint (…
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In the first decades of the twentieth century, the American multinational United Fruit Company, prominent in the production and sale of tropical fruits, found a way to deal with malnutrition among its workers in Costa Rica: it imported canned and processed foods from the United States. At the same time, the solution to high infant mortality in the banana plantation zone was the introduction of an artificial food developed by Nestlé. Years later, in Mexico, the government followed the “fortified” food trend, promoting the consumption of vitamin-enriched sugar.
No, obesity did not appear…
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The Institute of Drug Technology (Farmanguinhos/Fiocruz) is closer to starting Pediatric Praziquantel production, indicated for schistosomiasis, a parasitic disease that affects about 200 million people worldwide, half of whom are children. Result of the International Pediatric Praziquantel Consortium, the drug is in the clinical trials last phase. Pilot batches are expected to be produced in March 2022 and the product available in 2024.
It is a water-dispersible tablet, which facilitates its administration to children under the age of six. Until now, the medication available for this…
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Large-scale deforestation of the Amazon forest associated with climate change will increase the risk of exposure to extreme heat. Such levels of heat, which will be physiologically intolerable for the human body, will profoundly affect regions inhabited by highly vulnerable populations, according to a study published by researchers Beatriz Alves de Oliveira, of Fiocruz; Marcus Bottino and Paulo Nobre, both of the National Institute of Space Research (INPE); and Carlos Nobre, of the Institute for Advanced Studies of the University of São Paulo (IEA/USP). This is the first analysis of the…
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The Evandro Chagas National Institute of Infectious Diseases (INI/Fiocruz) is now open for enrollment, up to November 1, into the Fourth International Course on Immunohistochemistry, Molecular Pathology and Histopathology for the Diagnosis of Infectious Diseases. Coordinated by Rodrigo Caldas Menezes, Luiz Cláudio Ferreira and Leonardo Pereira Quintella, the training is aimed at healthcare professionals, especially those that work or wish to work in the field of pathological anatomy on the techniques of histopathology, immunohistochemistry and molecular pathology, focused on the…
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The COVID-19 pandemic was one of the main subjects discussed at two meetings that drew the attention of the entire world and of the region last week. While chiefs of state and of government debated the effects of the disease at the 76th General Assembly of the United Nations, at the 59th Board of Directors and 73rd Session of the Regional Committee of the World Health Organization (WHO) for the Americas, organized by the Pan-American Health Organization (PAHO), ministries of health discussed how to obtain a more equitable distribution of vaccines. With several issues in common, the agendas of…
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By means of its Immunobiological Technology Institute (Bio-Manguinhos), last Monday (September 27th) Fiocruz ended the production of the first batches called pre-validation batches of the national Active Pharmaceutical Ingredient (API) for the COVID-19 vaccine. The ingredient will now be submitted to quality control tests at the institution to then be sent to the final processing phase of the vaccine. The first pre-validation batch, which was produced early in September, is also under analysis.
The goal of the two pre-validation batches is to show that the process works as expected and, if…
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Mais de 5,2 milhões de crianças morreram antes que pudessem completar cinco anos no Brasil, entre 2006 e 2015. Esse número poderia ser ainda maior caso não houvesse programas de transferência de renda, como Bolsa Família, que ajudou a reduzir em 16% a mortalidade nessa faixa etária. Essa é a conclusão do estudo realizado usando métodos estatísticos e Big Data, no Centro de Integração de Dados e Conhecimento para Saúde (Cidacs/Fiocruz Bahia). O resultado foi publicado (28/9) na revista PLOS Medicine.
Os pesquisadores compararam os municípios de alta e baixa renda e entre aqueles onde há…
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Diseases that Brazilians are very familiar with, such as dengue fever, zika and chikungunya, are being directly affected by the pandemic, both with the transfer of human and material resources to the fight against COVID-19 and with possible undernotifications. But we can learn lessons from this experience, as shown by the 20th Advanced Seminaries on Global Health and Health Diplomacy of the Fiocruz Global Health Center (CRIS/Fiocruz), held last Thursday (September 23rd). And as indicated by the Challenges and opportunities to control arbovirus diseases in COVID-19 times webinar, this problem…
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The Immunobiological Technology Institute (Bio-Manguinhos/Fiocruz) was selected last Tuesday (September 21st) by the World Health Organization (WHO) as a hub for the development and production of vaccines using messenger RNA in Latin America. This Foundation unit was chosen due to the promising advancements in the technological development of an mRNA vaccine against Covid-19, currently in a pre-clinical stage. The initiative used resources of the Ministry of Health and of parliamentary amendments for its development.
The choice was the result of a worldwide call launched on April 16th, 2021…
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As part of the preparations for the new Brazilian expedition to Antarctica, Fiocruz donated 3,000 rapid tests to detect Sars-Cov-2 antigens to the Navy. The kits, produced by the Institute of Technology in Immunobiologicals (Bio-Manguinhos/Fiocruz), will be used to test the entire crew on board, on the support flights, the team at the Comandante Ferraz Antarctic Station and the researchers who will be part of the new trip - including the Fioantar team, which leaves in the next weeks. The Fiocruz's Antarctic program expeditions with researchers are being resumed, after the interruption last…
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A Swedish study with people infected by the Sars-CoV-2 and with subjects immunized with the Oxford/AstraZeneca (produced in Brazil by Fiocruz), Pfizer/BioNTech vaccines, and with people who were given one dose of each vaccine shows good protection 12 months after vaccination, against the so-called variants of concern. Submitted as preprint (without peer review), the research shows that two doses of the AstraZeneca vaccine result in the smallest reduction in effectiveness in neutralization assays against the Gamma and Beta variants, those with the most significant drops in effectiveness in all…
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Researcher Jorge Bermudez, chief of the Department of Medicines Policy and Pharmaceutical Services at the Sergio Arouca National School of Public Health (ENSP/Fiocruz, in the Portuguese acronym), is now a member of the Technical Advisory Group (TAG) created to advise the World Health Organization (WHO) in scientific, technical and strategic issues related to COVID-19 Technology Access Pool (C-TAP). C-TAP is a solidarity mechanism launched in May 2020 to facilitate timely, accessible and equitable access to COVID-19-related technologies. The only representative of Latin America in the…
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Women are the majority in the healthcare workforce. Yet they are far from leadership positions, face unequal pay, and are often victims of bullying and sexual harassment. If the panorama described in the webinar Women in Global Health, promoted by the Fiocruz Global Health Center (Cris/Fiocruz) on the last 15th, seems bleak, it also brings foci of hope: at the same time that it exacerbated these inequalities, the COVID-19 pandemic shed light on them, broadening the debate around the theme and the search for solutions.
Coordinated by the Fiocruz vice-president of Education, Information…
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The president of Oswaldo Cruz Foundation (Fiocruz), Nísia Trindade Lima, has been appointed to the Board of the Coalition for Epidemic Preparedness Innovations (CEPI). She becomes one of two representatives for Latin America on the Board. CEPI is an international organization, that aims to fund research projects to accelerate vaccines against epidemics.
CEPI has secured funding from over thirty governments, philanthropic institutions and private sector investors to date, with other twenty-five vaccine development partnerships…
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Last Wednesday, September 1st, Nísia Trindade Lima, president of Fiocruz, was granted the Knight Grade of France’s Legion of Honor (Ordre National de la Légion d'Honneur). She was graced with the honor as an acknowledgment of the Foundation’s president in the fields of Science and Health, especially regarding the actions undertaken by the institution in the fight against the COVID-19 pandemic. The ceremony, which took place at Praça Pasteur, at the Fiocruz Manguinhos campus, in Rio de Janeiro, was limited to a few guests, who followed strict social distancing protocols. The honor was given to…
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The world is ageing, and it is not only in the wealthiest countries. In Brazil, this matter has an aggravating factor: while more developed nations become rich first and then age, Brazil is ageing in poverty, warns Alexandre Kalache. The president of the International Longevity Centre in Brazil, who is a doctor, was the mediator in the webinar Ageing, demographic changes and the pandemic, of the Fiocruz Global Health Center (CRIS/Fiocruz), that showed the impact of COVID-19 on the matter on last Wednesday (September 1st).
It is not possible to talk about the pandemic’s impact on…
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Despite the restrictions imposed due to the pandemic, the team at the Laboratory for Clinical Research on Mycobacterioses of the Evandro Chagas National Institute of Infectology (INI/Fiocruz) considers 2021 a year of great advances. "Besides the adaptation to work in home office and the remote service implementation for patients, we have been contemplated in different national and international initiatives. This allows us to carry out new studies to improve the tuberculosis diagnosis and treatment, which is a serious public health problem in the country", said Valeria Rolla, head of the…
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A study conducted by Brazilian researchers shows how age influences the effectiveness of the two main immunizers used in the country against COVID-19. Submitted as a preprint in MedRxiv, the study Influence of age on effectiveness and duration of protection in the Oxford/AstraZeneca and CoronaVac vaccines involved more than 75 million immunized people, becoming the largest study conducted with the two immunizers and may serve as a basis for guiding public health decisions, including the need for additional doses or booster doses.
Coordinated by Manoel Barral-Netto, a researcher at…
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The Observatory of Climate and Health of the Institute of Scientific and Technological Communication and Information in Health (ICICT/Fiocruz), in a partnership with InfoAmazonia and the Federal University of Acre, invests in the project Engolindo Fumaça (Swallowing Smoke), a research on the impacts of the pollution resulting from wildfires in the Amazon during the COVID-19 pandemic. The forest fires and wildfires caused for deforestation have been breaking records in recent years. In 2020, a combination of the COVID-19 pandemic and one of the most severe cycles of wildfires and…
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The COVID-19 pandemic has exposed the high dependence of Latin America and the Caribbean on imported consumables and technologies for health, including vaccines. As a response to this issue, member states of the Pan-American Health Organization (PAHO) launched last Friday (August 27th) a collaborative platform that brings together governments and interested parties of the public and private sectors, taking up the mission of facilitating the expansion of services and production related to health in the Americas.
“Latin America is in a vulnerable position as it depends on other countries’…
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An unprecedented survey by the Oswaldo Cruz Foundation (Fiocruz) shows that the number of COVID-19 deaths in Brazil in 2020 was 18.2% higher than recorded. The analysis indicated that there were 230,452 deaths from the disease last year, not 194,949. The results of the study, funded by the Fiocruz Program to Foster Innovation (Inova Fiocruz), will be published in the Fiocruz COVID-19 Monitoring panel.
Coordinator of the study, Cristiano Boccolini explains that the data previously released by the Ministry of Health's Mortality Information System (SIM, acronym in Portuguese) were not wrong and…
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The release of Aedes aegypti mosquitoes carrying Wolbachia in Niterói, in the state of Rio de Janeiro, which began as a pilot action in Jururuba, in 2015, and covered 75% of the city’s territory, has already yielded positive effects. Data released this Thursday (August 26th) by the Wolbachia Method, an initiative of the World Mosquito Program (WMP) led by Fiocruz in Brazil, indicate a reduction of about 70% of cases of dengue fever, 60% of chikungunya, and 40% of zika in the areas where the entomological intervention took place.
Niteroi's mayor, Axel Grael (right), Valcler Rangel from Fiocruz…
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