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The rapid spread of some Sars-CoV-2 variants has been associated with reports of COVID-19 reinfection, based, for example, on the P.1 high prevalence in the first two months after its emergence. Given this scenario, researchers from Fiocruz Pernambuco and Foundation's Genomics Network members sought to verify what the real mechanisms behind reinfection might be. The initial hypothesis was that a greater competence of the new variants would bind to human host cells, but the result pointed in a different direction. According to the study coordinator and Fiocruz Pernambuco researcher, Roberto…
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Beatriz Grinsztejn, head of the INI’s Laboratory of Clinical Research on STDs and AIDS, was granted last Wednesday (March 19) the Ward Cates Spirit Award by the HIV Prevention Tests Network (HPTN). Anthony Fauci, director of the National Institute of Allergies and Infectious Diseases (NIAID) of the United States, attended the event.
The award was given by Myron Cohen, the main investigator of the network. More than one thousand researchers with links to the HPTN cast ballots to elect this year’s winner. “Beatriz Grinsztejn joined us leading the HPTN 052 study in Brazil (Prevention of Sexual…
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If the COVID-19 pandemic has had a devastating effect worldwide, recovery provides an opportunity for long-overdue changes to finally happen. It is not enough to think of returning to normality as it was before, because this would not be good for anyone, it is necessary to correct the course and direct science, technology, and innovation towards meeting social, environmental, and health objectives. It was on this line of reflection that the various presentations converged in the debate held on Tuesday (May 18), organized by the Oswaldo Cruz Foundation (Fiocruz) and the Global Conferences on…
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The Observatory of Sustainable and Healthy Territories of Bocaina (OTSS), a partnership between Fiocruz and the Traditional Communities Forum (FCT), was appointed as one of the 10 most innovative initiatives for the Sustainable Development Goals (SDGs) implementation in Brazil by 2021. The selection was announced by the Civil Society Working Group for Agenda 2030 (WG 2030 Agenda) and the Institute for Democracy and Sustainability (IDS Brasil).
"This award shows the correctness of the OTSS territorial governance strategy and the effectiveness of the solutions that have been developed for the…
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A study coordinated by the Oswaldo Cruz Foundation (Fiocruz) is helping to understand why some critically ill patients submitted to mechanical ventilation manage to leave the ICU, while others do not survive. The research indicates that the presence of the human endogenous retrovirus K (HERV-K) is associated not only with worsening disease but also with early mortality.
From March to December 2020, the study Human endogenous retrovirus K activation in the lower respiratory tract of severe COVID-19 patients associates with early mortality followed 25 critically ill patients who required…
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The dengue virus is one of the greatest threats to public health in globe tropical regions, and especially in Brazil, where annual epidemics lead to thousands of Brazilians sickness. In the year 2019 alone, there were 2.1 million cases. However, something very intriguing happened in the years 2017-2018, right after the zika, dengue and chikungunya virus’s triple epidemic in 2016. Dengue fever case numbers were reported well below average until its resurgence in 2019.
In the search for an answer to this phenomenon, a study was carried out in cooperation by researchers from Fiocruz Pernambuco…
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A mixture of expectation and hope took over Botucatu, in the interior of São Paulo, this weekend. The city was chosen to be the stage for an unprecedented research that kicked off last Sunday (5/16), with the mass vaccination against COVID-19 of the entire adult population. More than 63,000 Botucatu residents were immunized in just one day, exceeding the expectation that 60,000 people would receive the first dose this Sunday. Minister of Health Marcelo Queiroga participated in the immunization process in the municipality, administering the first dose of the vaccine to 57-year-old Suze Helena…
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The name of the most recent seminar of the Fiocruz Global Health Center (CRIS in the Portuguese acronym), last Wednesday (May 12th), came from a question: Ibero-America - A New Space for Health Diplomacy? And it ended with an answer. For most of the event’s attendees, diplomats and experts on both sides of the Atlantic, the pandemic accelerated a process of cooperation that had already been taking place in the region, put health under the spotlight, and showed that a common response is needed for a common problem. “It is not the diplomacy of the disease or the vaccine. It is the diplomacy of…
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There is little data available on the mental health of young indigenous people. In this context, between December 2020 and January 2021, scientists from the Research Center Leônidas & Maria Deane (Fiocruz Amazonia) carried out a diagnostic study that involved eight regions of the Amazon and that resulted in a better understanding of the effects of COVID-19 in this population group. “The study focused on the understanding of the knowledge, the attitudes and the practices (KAP) of young people on mental health during this pandemic period. The results show that indigenous…
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Fiocruz is taking part of the survey COVID-19: our care, our actions, their effects, with the goal of getting to know better the treatments and preventive actions that people from all over the world have been experiencing in the context of the disease. Spearheaded by the Antenna Foundation, a Swiss NGO that offers technological and medical solutions to populations in need, the survey boasts the collaboration of universities and research institutions from 13 countries. In Brazil, Fiocruz Bahia is the partner in charge of the project led by the institution’s Committee of Ethics in Research (CEP…
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Although studies suggest that children and adolescents attending summer camps and social events may carry COVID-19 into their homes, work by researchers at the Oswaldo Cruz Foundation (Fiocruz), the University of California (UCLA), and the London School of Hygiene and Tropical Medicine (LSHTM) indicates that they more often become infected by adults than act as transmitters.
A preview of the article SARS-CoV-2 Infection Dynamics in Children and Household Contacts in a Slum in Rio de Janeiro, to be published in Pediatrics, Official Journal of the American Academy of Pediatrics, explains that…
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Establishing a dialog between scientific development and social development was one of the proposals presented by Fiocruz’s president, Nísia Trindade Lima, in the event What Needs to be Done?: Biomedical and Public Health Research in Brazil and the US Post-COVID, promoted by Yale University. The president emphasized the social nature of the pandemic and the need to consider the organization of social protection as a fundamental axis for post-COVID-19 recovery.
“The Covid-19 pandemic is showing a high scientific response, but it reveals a deep inequality among countries, and within…
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“If you ask me whether we were prepared for this pandemic, I say that, obviously, we were not. If the question is whether we should be prepared for the next pandemics, I clearly say yes. We heard a lot of talk about the resilience and strengthening of healthcare systems, but we must turn speeches into actions.” This was one of the statements made by Carissa Etienne, director of the Pan American Health Organization (PAHO), last Friday (April 30), in her presentation at the Advanced Seminars on Global Health and Health Diplomacy, organized by Fiocruz Global Health Center (CRIS). The event…
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Promoting the discussion on new strategies to increase research, technological development, and innovation at the Oswaldo Cruz Foundation (Fiocruz), with speakers from development agencies and national and international academic centers dedicated to new methodologies for the governance of science and technology, technological and scientific prospecting, knowledge and innovation management. It is for this purpose that the Oswaldo Cruz Institute (IOC/Fiocruz) will hold the 1st International Symposium on Research & Innovation by IOC from May 17 to May 19, which will also be broadcast in…
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The pandemic brought challenges, but also opportunities, according to lecturers on the 6th annual Multi-stakeholder Forum on Science, Technology, and Innovation for the Sustainable Development Goals (SDG), also known as the STI Forum. In Lessons from the COVID-19 Pandemic, the forum’s first session, on Tuesday May 4th, specialists on the fields of sciences, technology and economics analyzed the scenario and looked for ways to recover and prevent a new global sanitation crisis. Among them was the President of Fiocruz, Nísia Trindade Lima. The Foundation was also present through Paulo Gadelha’s…
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The pandemic brought challenges, but also opportunities, according to lecturers on the 6th annual Multi-stakeholder Forum on Science, Technology, and Innovation for the Sustainable Development Goals (SDG), also known as the STI Forum. In Lessons from the COVID-19 Pandemic, the forum’s first session, on Tuesday May 4th, specialists on the fields of sciences, technology and economics analyzed the scenario and looked for ways to recover and prevent a new global sanitation crisis. Among them was the President of Fiocruz, Nísia Trindade Lima. The Foundation was also present through Paulo Gadelha’s…
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The director of Fiocruz Minas, Zélia Profeta, was invited to be a member of the Council on the Economics of Health for All, recently created by the World Health Organization (WHO). The invitation was sent by WHO’s Director-General Tedros Adhanom and Professor Mariana Mazzucato of University College London, who will coordinate the Council.
The creation of the Council on the Economy of Health for All was announced in November 2020, during the 73rd World Health Assembly. The proposal is to put the concept of “health for all” at the center of discussions when thinking about creation of value and…
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A study by Fiocruz and WWF-Brasil shows that the wildfires in the Amazon were responsible for the increase in the percentages of hospitalizations due to respiratory problems in the last 10 years (2010-2020) in states with higher numbers of hot spots: Pará, Mato Grosso, Rondônia, Amazonas and Acre. These hospitalizations cost the public treasury almost 1 billion. The survey also points out that the association of the pandemic situation with forest wildfires in the Amazon may have aggravated the health situation of the legal Amazon population, because the pollutants from the wildfires can cause…
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Two drugs used against hepatitis C have been proven effective in inhibiting Sars-CoV-2 replication in cells in laboratory studies. The trial is now entering its phase 2: tests in patients. The results of the first phase of the trial, led by researchers of the Oswaldo Cruz Foundation (Fiocruz), were published on April 21 in a paper for the Journal of Antimicrobial Chemotherapy, by Oxford Academic. The results of phase 2 will likely be known in the second semester of 2021.
Images show the action of sofosbuvir and daclastavir in a cell infected with Sars-CoV-2
The trial, which began last week,…
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The Presidency of the Oswaldo Cruz Foundation (Fiocruz) signed, on April 20, an international cooperation agreement with the Institute of Global Health of Barcelona (ISGlobal), to establish the basis to implement a joint work plan for the upcoming years. The two institutions have worked together at previous occasions in different research projects and scientific publications. However, the new Memorandum of Understanding formalizes the association and strengthens the intention of the institutions to promote public health and collaboration in important fields, such as neglected tropical…
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Published on April 24, the Bulletin of the Fiocruz COVID-19 Observatory, referring to Epidemiological Weeks (EW) 14 and 15, between 4 and 17 April, presents a general overview of the Covid-19 situation in the country and its implications. The new edition shows that the pandemic is hitting younger people. The number of cases and deaths by Covid-19 per age group shows that the differential increase per age group is steady. According to the analysis, the younger age group, from 20 to 29 years old, was the one with the higher number of deaths: 1,081.82%. The age group from 40 to 49 years old (1,…
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A study by researchers of the Oxford University shows that the risk of cerebral venous thrombosis (CVT) in people with COVID-19 is considerably higher than in those who have been vaccinated with mRNA (messenger RNA) vaccines, such as those by Pfizer and Moderna. In addition to mRNA vaccines, the analysis also included the Oxford/AstraZeneca immunizer, produced in Brazil by the Oswaldo Cruz Foundation (Fiocruz).
The survey Cerebral venous thrombosis: a retrospective cohort study of 513,284 confirmed COVID-19 cases and a comparison with 489,871 people receiving a COVID-19 mRNA vaccine brought…
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The emergence of COVID-19 and the entire context of the pandemic humankind has been facing has raised an alert for the possible appearance of other emerging and re-emerging epidemics that may occur as a consequence of the interferences suffered by Brazilian biomes — deforestation and destruction of ecosystems. In a paper published recently in Genetics and Molecular Biology, researchers highlight that the Amazon’s environmental vulnerability when faced with degrading actions the biome has been suffering is a risk to the health of populations, especially when it carries the possibility of the…
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Remembered for the second consecutive year, World Chagas Disease Day was marked in Fiocruz on 14/4, with an event that had not only tributes to those who helped in the research and fight against the disease, but also with the look on the future. In addition to the tributes to the researchers of the institution Zilton Andrade and José Rodrigues Coura, who have died, there was the agreement with Unitaid of CUIDA Chagas virtual signing, a project that aims to eliminate the disease congenital transmission in Latin American countries. The initiative, which includes co-financing from the Brazilian…
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A “pandemic of inequalities”, which denies people access to water to wash their hands, is one of the factors that have worsened the dissemination of Sars-CoV-2 in Latin America and in the Caribbean. This is the assessment of the UN High Commissioner for Human Rights and former president of Chile, Michelle Bachelet. A physician herself, last Thursday (April 15) she opened the Advanced Seminaries on Global Health and Health Diplomacy of the Center of International Relations in Health (Cris/Fiocruz).
“Those who were already more vulnerable before, such as women, were those most affected by the…
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The Conference On Expanding Africa’s Vaccine, organized by the African Union and the Centers for Disease Control in Africa (CDC Africa), held on 12 and 13/4, had the Oswaldo Cruz Foundation (Fiocruz) president as one of the speakers on Tuesday. During Session 8, on the Partnership with Foundations for Vaccine Production, Nísia reaffirmed Fiocruz's commitment to a South-South agenda to support the needs of the African continent in strengthening its health system, preparing for disease emergencies, and providing the population with access to medical care.
The session, moderated by Winnie…
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Many viruses can hamper coagulation, including those that cause dengue fever and yellow fever. In more severe cases, they may lead to bleeding. This is why these diseases are considered hemorrhagic viral fevers. In a paper recently published in the science magazine “Memórias do Instituto Oswaldo Cruz”, a group of ten researchers argues that the new coronavirus (SARS-CoV-2) should be the first agent recognized as acting in the opposite fashion, by increasing the formation of blood clots (also called thrombi) that can obstruct blood flow. Taking into account available evidence of…
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